Journal Club - Recent Additions

August - 2020

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Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock The ACTS Randomized Clinical Trial

A Moskowitz, D Huang, P Houe et al for the ACTS Clinical Trial Investigators JAMA, 2020, 324(7):642-650

Comment

The ACTS RCT provides further evidence suggesting a vitamin C “cocktail” does not improve outcomes in sepsis.

As a refresher;

  • VITAMINS trial 2019 JAMA

August



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