April - 2020
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Compassionate Use of Remdesivir for Patients with Severe Covid-19Jonathan Grein, Norio Ohmagari, Daniel Shin et al, NEJM, 2020, Online first This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
April |
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Remdesivir is a prodrug of a nucleotide analogue that is intracellularly metabolized to an analogue of ATP that inhibits viral RNA polymerases. It has broad-spectrum antiviral activity including filoviruses (e.g., Ebola) and coronaviruses (e.g., SARS-CoV and MERS-CoV), with some...