October - 2019
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Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock -The SEPSIS-ACT Randomized Clinical TrialPierre-Francois Laterre, Scott M. Berry, Allan Blemings, et al for the SEPSIS-ACT Investigators JAMA, 2019, 322(15):1476-1485 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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The rationale for this trial is that norepinephrine is not always effective at restoring blood pressure in septic shock, and has potential side-effects including myocardial and peripheral ischemia. As a result of this there has been a search for other...