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September - 2017

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Showing Journal 6 of 7


Applying Precision Medicine to Trial Design Using Physiology. Extracorporeal CO2 Removal for Acute Respiratory Distress Syndrome

E Goligher, M Amato, A Slutsky Am J Resp Crit Care Med, 2017, 196(5);558-568

Comment

This critical care perspective applies the question of the limitations of the traditional gold standard RCT trial design, to the modern question of ECCO2R efficacy. The authors start by reminding us that “failure to demonstrate benefit in an RCT may be attributable to the absence of...


September



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