October - 2016
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Levosimendan for the Prevention of Acute Organ Dysfunction in SepsisA Gordon, G Perkins, M Singer, et al NEJM, 2016, 375:1638-1648 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This study, the LeoPARDS (Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis) trial, describes the effect of levosimendan, the calcium sensing ino-dilator, in the setting of severe sepsis, with the goal to prevent organ dysfunction. The rationale was the...