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December - 2015

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Showing Journal 7 of 7


Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care

TJ Iwashyna, JF Burke, JB Sussman, et al Am J Resp Crit Care Med, 2015, 192(90;1045-1051

Comment

This is a very interesting article that discusses and dissects the problem of external applicability of results of clinical trials. It begins with the oft-cited premise that results of a well-conducted RCT, if beneficial, should be applied to the same population broadly. So, what...


December



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