May - 2014
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Lorazepam vs Diazepam for Pediatric Status Epilepticus: A Randomized Clinical TrialJames M. Chamberlain, Pamela Okada, Maija Holsti, et al JAMA, 2014, 311(16):1652-1660 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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Status epilepticus requires rapid control to prevent brain injury. Diazepam is approved by the FDA for treatment of convulsive status epilepticus, but lorazepam is not, despite proposed potential advantages. This RCT compared lorazepam (0.1 mg/kg IV) to diazepam (0.2 mg/kg...