October - 2013
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Induced Hypothermia in Severe Bacterial Meningitis A Randomized Clinical TrialBruno Mourvillier, Florence Tubach, Diederik van de Beek, et al. JAMA, 2013, Published online October 08, 2013. doi:10.1001/jam This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This open-label, multicenter, RCT tested the hypothesis that induced hypothermia (cooled to 32-34C for 48-hours) improved outcomes in adult patients with severe bacterial meningitis. They found that this was not the case, and that moderate hypothermia may be harmful, with the trial...