July - 2013
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Sodium Bicarbonate Infusion to Reduce Cardiac Surgery–Associated Acute Kidney Injury: A Phase II Multicenter Double-Blind Randomized Controlled TrialShay McGuiness, Rachael Parke, Rinaldo Bellomo, Frank van Haren, Michael Bailey Crit Care Med, 2013, 41:1599–1607 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This phase IIb multicenter double-blind RCT reports on perioperative alkalinasation of bood and urine (IV NaHCO3) compared to standard care (IV NaCl) to prevent AKI in cardiac surgery patients with an increased risk of AKI. In 417 patients they found the treatment was effectively delivered...