June - 2013
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Time to Treatment With Intravenous Tissue Plasminogen Activator and Outcome From Acute Ischemic StrokeJeffrey L. Saver, Gregg C. Fonarow, Eric E. Smith, et al JAMA, 2013, 309(23):2480-2488 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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Although RCTs of tPA in acute ischaemic stroke suggest time-dependent benefit, there is ongoing uncertainty about external validity, and applicability to non-clinical trial settings. This large US stroke registry looks at outcomes of 58 353 patients with ischaemic stroke who received tPA...