April - 2013
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Factors Predisposing to Coma and Delirium: Fentanyl and Midazolam Exposure; CYP3A5, ABCB1, and ABCG2 Genetic Polymorphisms; and Inflammatory FactorsY Skrobik, C LEger, M Cossette, et al Crit Care Med, 2013, 41(4);999-1008 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
April |
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This study is worth a second look, as it tries to separate out factors that contribute to coma or delirium. They look at the effects of common sedatives (midazolam, fentanyl), covariates (organ dysfunction, age, BMI), delirium risk factors, administration of drugs that affect CYP450...