April - 2013
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Effect of an Investigational Vaccine for Preventing Staphylococcus aureus Infections After Cardiothoracic Surgery - A Randomized TrialVance G. Fowler, Keith B. Allen, Edson D. Moreira, et al JAMA, 2013, 309(13):1368-1378. This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This is a fairly unexpected addition to the critical care literature - a double blind RCT examining the effect of a novel vaccine (V710) given IM preoperatively, on serious postoperative S aureus infection rates following cardiac surgery.
The primary outcome was bacteraemia and deep...