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November - 2012

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Associations Between Aldosterone Antagonist Therapy and Risks of Mortality and Readmission Among Patients With Heart Failure and Reduced Ejection Fraction

Adrian F. Hernandez, Xiaojuan Mi, Bradley G. Hammill, et al. JAMA, 2012, 308(20):2097-2107

Comment

This observational trial examines translation of the clear evidence of benefit from, aldosterone antagonists in heart failure with reduced EF (HFREF), into safety and efficacy in clinical practice. The authors were particularly interested in older, sicker, minority group patients who...


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