November - 2012
| Previous Next | Showing Journal 21 of 23 |
Empirical Evaluation of Very Large Treatment Effects of Medical InterventionsTiago V. Pereira, Ralph I. Horwitz, John P. A. Ioannidis JAMA, 2012, 308(16):1676-1684 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
November |
Previous Comments
No Comments yet.
Comment
This review of the Cochrane Database of Systematic Reviews (DSR) sums up the message in the conclusion - Most large treatment effects emerge from small studies, and when additional trials are performed, the effect sizes become typically much smaller. Well-validated large effects are...