October - 2012
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Daily Sedation Interruption in Mechanically Ventilated Critically Ill Patients Cared for With a Sedation Protocol: A Randomized Controlled TrialS Mehta, L Burry, D Cook, for the SLEAP Investigators and the Canadian Critical Care Trials Group JAMA, 2012, 308(19):doi:10.1001/jama.2012.13872 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This 430 patient, 14 centre, prospective Canadian RCT compared a sedation protocol to sedation protocol + daily interruption of sedation, and found no difference in duration of mechanical ventilation. The protocol + interruption group did have higher mean daily dose of midazolam,...