July - 2012
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Effect of Adenosine-Regulating Agent Acadesine on Morbidity and Mortality Associated With Coronary Artery Bypass Grafting The RED-CABG Randomized Controlled Trialthe RED-CABG Steering Committee and Investigators JAMA, 2012, 308(2):157-164 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This large multi-centre RCT of acadesine (adenosine regulating agent) delivered by cardioplegia in intermediate to high-risk nonemergency on-pump CABG was stopped for futility at 3080 of 7500 patients. The OR of the primary outcome, composite all-cause mortality, nonfatal stroke, or...