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March - 2012

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Showing Journal 11 of 18


Induction of prehospital therapeutic hypothermia after resuscitation from nonventricular fibrillation cardiac arrest

Bernard SA, Smith K, Cameron P, Masci K, Taylor DM, Cooper DJ, Kelly AM, Silvester W; Rapid Infusion of Cold Hartmanns (RICH) Investigators. Critical Care Medicine, 2012, 40(3):747-53

Comment

Does it matter how fast patients are cooled following resuscitation from out of hospital cardiac arrest?  

According to this prospective randomised controlled trial, there is no benefit from initiating this intervention pre-hospital.

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March



Previous Comments

I think its interesting that the two main trials that demonstrate a meaningful impact used surface cooling. There have been a lot of studies that compare rate of cooling using different methods, particularly ice cold fluids, and assume that there is a similar effect to surface cooling. I'm not aware of any evidence that this is so. Trying to conclude that there is an effect in the group with a cardiac cause do better is stretching things a bit. This is hypothesis generating at best, but I'm not sure you can even call it that.
Darren Cable-15 Mar, 2012 10:10:16 AM