Journal Club - Recent Additions

March - 2012

Previous Next    

Showing Journal 16 of 18


Dopamine versus norepinephrine in the treatment of septic shock: A meta-analysis*

De Backer D, Aldecoa C, Njimi H, Vincent JL. Critical Care Medicine, 2012, 40(3):725-30.

Comment

It seems everyone is lining up for a free swing at dopamine.  This latest systematic review finds what we all know - dopamine has no role in sepsis.


March



Previous Comments

Is there anything to be gained by continuing to review the role of dopamine in clinical practice?
James O'Connor-03 Mar, 2012 03:33:36 PM

Does anyone in Australia actually use dopamine for anything? This is something that has refused to die in some parts of the world for reasons that I can't fathom - there was sufficient evidence in the 1990s to abandon dopamine, and the clincher was the ANZICS CTG dopamine trial published in 2000. Unfortunately the first edition of the Surviving Sepsis Guidelines gave dopamine a boost because of its historical use in the USA. Also think about those parts of the world where noradrenaline is expensive and difficult to find. What is so wrong with adrenaline (cheap and readily available)? CAT, CATS and SOAP all support this statement! Ian Seppelt Ian Seppelt
Ian Seppelt-12 Mar, 2012 05:09:32 PM