Journal Club - Recent Additions

January - 2012

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Showing Journal 8 of 18


Serum Potassium Levels and Mortality in Acute Myocardial Infarction

A Goyal, J Spertus, K Gosch, L Venkitachalam, P Jones, G Van den Berghe, M Kosiborod. JAMA, 2012, 307(2):157-164

Comment

This large retrospective cohort study of patients with biomarker confirmed AMI reported lowest mortality when K was between 3.5-4.5. This was significant and persisted after multivariate adjustment. The highest rates of ventricular arrhythmias were seen with K's of less than 3.0 or...


January



Previous Comments

Interesting paper - what is the link to mortality? Is it that dyskalaemia causes problems such as arrhythmias? Or is it an independent marker of background pathology not explained by the regression analysis - such as diuretic use for heart failure causing hypokalaemia, or acute renal impairment resulting in hyperkalaemia?
Todd Fraser-28 Jan, 2012 10:34:12 AM

I suspect you're right...
Darren Cable-29 Jan, 2012 04:20:56 PM