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December - 2011

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Showing Journal 6 of 17


Time course of organ failure in patients(with septic shock treated with hydrocortisone: results of the Corticus study

R. Moreno, C. L. Sprung, D. Annane, et al ICM, 2011, 37:1765-1772

Comment

It should be common knowledge that CORTICUS was a negative study. Although it was the largest study on this subject, there were a number of limitations. Perhaps the most important was premature termination (stopped at 500, not 800 as planned), due to expiration of funding and slow recruitment,...


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