January - 2011
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Very early hypothermia induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trialProf Guy L Clifton, Alex Valadka , David Zygun et al. Lancet Neurology, 2011, Lancet Neurology, Volume 10, Issue 2, Pages 131 - This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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This frustratingly small trial of 97 patients was conducted over 4 years and terminated early due to suggestion of futility. 52 patients were enrolled in the treatment arm, which involved cooling to 33 degrees for 48 hours, while 45 were maintained at normothermia.
The...