January - 2008
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Intensive Insulin Therapy and Pentastarch Resuscitation in Severe SepsisF Brunkhorst, C engel. F Bloos, et al for the German Competence Network Sepsis (SepNet) NEJM, 2008, 358:125-139 This page is only available to Crit-IQ subscribers. To view the rest of this review and gain access to our vast array of critical care teaching tools including podcasts, vodcasts, modules, exam preparation tools, teaching aids and much more, login here, or Become a Member to register |
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In 2008 the international review board stopped the German SepNet groups IIT in severe sepsis trial after 537 patients were enrolled because of a high incidence of hypoglycaemia in the IIT group (17.6% vs 4.5%). At the time of stopping there was no difference in mortality or...