Journal Club - Recent Additions

November - 2020

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Showing Journal 3 of 4

Efficacy of Tocilizumab in Patients Hospitalized with Covid-19

J.H Stone, M.J Frigault, N.J Serling-Boyd, et al for the BACC Bay Tocilizumab Trial Investigators New Eng J Med, 2020, 10.1056/NEJMoa2028836


Severe COVID-19 infection is characterised by markedly abnormal inflammatory markers, including IL6, ferritin and CRP. Also, higher serum IL-6 concentrations are associated with higher levels of SARS-CoV-2 viraemia, prolonged viral RNS sheeting, progression to MV and death. This RCT...


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